Publisher Correction: Human heart-forming organoids recapitulate early heart and foregut development
نویسندگان
چکیده
منابع مشابه
Chicken NKx2–8, a novel homeobox gene expressed during early heart and foregut development
cNkx2-8 represents a novel member of the NK2-family transcription factors. The gene contains three highly conserved regions, the TN-, NK2-, and homeodomains which are diagnostic for this group of proteins. cNkx2-8 is expressed during chick embryogenesis in ventral foregut endoderm, myocardial mesoderm, epithelium of the branchial arches and the dorsal mesocardium. While cNkx2-8 expression parti...
متن کاملCerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain.
Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral organoids and human fetal brain, using genome-wide, base resolution DNA methylome and transcripto...
متن کاملHuman cerebral organoids recapitulate gene expression programs of fetal neocortex development.
Cerebral organoids-3D cultures of human cerebral tissue derived from pluripotent stem cells-have emerged as models of human cortical development. However, the extent to which in vitro organoid systems recapitulate neural progenitor cell proliferation and neuronal differentiation programs observed in vivo remains unclear. Here we use single-cell RNA sequencing (scRNA-seq) to dissect and compare ...
متن کاملA Publisher with an Open Heart
Discussions among the Directors of The Company of Biologists have focused in recent years on the ‘pain to publish’ experienced by authors – and from these discussions grew the idea of a journal that could lessen that pain. So last year, the Company conducted a survey of authors in the communities associated with its three established journals: Development, Journal of Cell Science and The Journa...
متن کاملMetabolic gene profile in early human fetal heart development.
The primitive cardiac tube starts beating 6-8 weeks post fertilization in the developing embryo. In order to describe normal cardiac development during late first and early second trimester in human fetuses this study used microarray and pathways analysis and created a corresponding 'normal' database. Fourteen fetal hearts from human fetuses between 10 and 18 weeks of gestational age (GA) were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2021
ISSN: 1087-0156,1546-1696
DOI: 10.1038/s41587-021-00960-1